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Environmental Electrophile-Mediated Toxicity in Mice Lacking Nrf2, CSE, or Both
BACKGROUND: Transcription factor Nrf2 (nuclear factor-erythroid 2-related factor 2) plays a key role in detoxification of electrophiles via formation of glutathione (GSH) adducts and subsequent excretion into extracellular spaces. We found that reactive sulfur species (RSS), such as cysteine persulf...
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| Publicado no: | Environ Health Perspect |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Environmental Health Perspectives
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6794492/ https://ncbi.nlm.nih.gov/pubmed/31166132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP4949 |
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