Loss of IL-10 Promotes Differentiation of Microglia to a M1 Phenotype

Microglia represent the primary resident immune cells of the central nervous system (CNS) and modulate local immune responses. Depending on their physiological functions, microglia can be classified into pro- (M1) and anti-inflammatory (M2) phenotype. Interleukin (IL)-10 is an important modulator of...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Laffer, Björn, Bauer, Dirk, Wasmuth, Susanne, Busch, Martin, Jalilvand, Tida Viola, Thanos, Solon, Meyer zu Hörste, Gerd, Loser, Karin, Langmann, Thomas, Heiligenhaus, Arnd, Kasper, Maren
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794388/
https://ncbi.nlm.nih.gov/pubmed/31649508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00430
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