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Polatuzumab Vedotin: First Global Approval
Polatuzumab vedotin (polatuzumab vedotin-piiq; Polivy™) is an antibody–drug conjugate comprising a monoclonal antibody against CD79b (a B cell receptor component) covalently conjugated to the anti-mitotic cytotoxic agent monomethyl auristatin (MMAE) via a cleavable linker. After binding to CD79b on...
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| Udgivet i: | Drugs |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer International Publishing
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6794237/ https://ncbi.nlm.nih.gov/pubmed/31352604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40265-019-01175-0 |
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