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Chromatin decondensation by FOXP2 promotes human neuron maturation and expression of neurodevelopmental disease genes

Forkhead box P2 (FOXP2) is a transcription factor expressed in the human brain that peaks during fetal development, and disruption in its ability to regulate downstream target genes leads to vulnerability to neurodevelopmental disorders. However, the mechanisms by which FOXP2 exerts regulatory contr...

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Publicat a:Cell Rep
Autors principals: Hickey, Stephanie L., Berto, Stefano, Konopka, Genevieve
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794152/
https://ncbi.nlm.nih.gov/pubmed/31067457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.04.044
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