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The S52F FOXF1 Mutation Inhibits STAT3 Signaling and Causes Alveolar Capillary Dysplasia

Rationale: Alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV) is a lethal congenital disorder causing respiratory failure and pulmonary hypertension shortly after birth. There are no effective treatments for ACDMPV other than lung transplant, and new therapeutic approaches ar...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Respir Crit Care Med
Prif Awduron: Pradhan, Arun, Dunn, Andrew, Ustiyan, Vladimir, Bolte, Craig, Wang, Guolun, Whitsett, Jeffrey A., Zhang, Yufang, Porollo, Alexey, Hu, Yueh-Chiang, Xiao, Rui, Szafranski, Przemyslaw, Shi, Donglu, Stankiewicz, Pawel, Kalin, Tanya V., Kalinichenko, Vladimir V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794119/
https://ncbi.nlm.nih.gov/pubmed/31199666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201810-1897OC
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