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Neurotrophin-3 Administration Attenuates Deficits of Pyridoxine-Induced Large-Fiber Sensory Neuropathy

Chronic treatment of adult rats for 2–3 weeks with high doses of pyridoxine (vitamin B(6)) produced a profound proprioceptive loss, similar to that found in humans overdosed with this vitamin or treated with the chemotherapeutic agent cisplatin. Pyridoxine toxicity was manifest as deficits in simple...

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Pubblicato in:J Neurosci
Autori principali: Helgren, Maureen E., Cliffer, Kenneth D., Torrento, Kim, Cavnor, Chris, Curtis, Rory, DiStefano, Peter S., Wiegand, Stanley J., Lindsay, Ronald M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793704/
https://ncbi.nlm.nih.gov/pubmed/8987762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-01-00372.1997
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