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Role of the Nucleus Raphe Magnus in Antinociception Produced by ABT-594: Immediate Early Gene Responses Possibly Linked to Neuronal Nicotinic Acetylcholine Receptors on Serotonergic Neurons

Recently, a novel cholinergic channel modulator, (R)-5-(2-azetidinylmethoxy)-2-chloropyridine (ABT-594), was shown to produce potent analgesia in a variety of rodent pain models when administered either systemically or centrally into the nucleus raphe magnus (NRM). The purpose of the present study w...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Bitner, R. Scott, Nikkel, Arthur L., Curzon, Peter, Arneric, Stephen P., Bannon, Anthony W., Decker, Michael W.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793487/
https://ncbi.nlm.nih.gov/pubmed/9651224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-14-05426.1998
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