Brain Dopamine Neurotoxicity in Baboons Treated with Doses of Methamphetamine Comparable to Those Recreationally Abused by Humans: Evidence from [(11)C]WIN-35,428 Positron Emission Tomography Studies and Direct In Vitro Determinations

The present study sought to determine whether doses of methamphetamine in the range of those used recreationally by humans produce brain dopamine (DA) neurotoxicity in baboons and to ascertain whether positron emission tomography (PET) imaging with the DA transporter (DAT) ligand [(11)C]WIN-35,428 (...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Villemagne, Victor, Yuan, Jie, Wong, Dean F., Dannals, Robert F., Hatzidimitriou, George, Mathews, William B., Ravert, Hayden T., Musachio, J., McCann, Una D., Ricaurte, George A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1998
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793413/
https://ncbi.nlm.nih.gov/pubmed/9412518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-01-00419.1998
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