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Long-Term Antidepressant Treatments Result in a Tonic Activation of Forebrain 5-HT(1A) Receptors

We report here the first direct functional evidence of an increase in the tonic activation of postsynaptic 5-HT(1A) receptors by antidepressant treatments. Because 5-HT(1A) receptor activation hyperpolarizes and inhibits CA(3) pyramidal neurons in the dorsal hippocampus, we determined, using in vivo...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Haddjeri, Nasser, Blier, Pierre, de Montigny, Claude
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793307/
https://ncbi.nlm.nih.gov/pubmed/9822768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-23-10150.1998
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