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Disruption of Mitochondrial Respiration Inhibits Volume-Regulated Anion Channels and Provokes Neuronal Cell Swelling

Hypoxia and inhibitors of mitochondrial respiration impair the regulatory volume decrease (RVD) of cerebellar granule neurons after hypotonic swelling. RVD is linked to the opening of volume-regulated anion channels (VRACs). VRACs are outwardly rectifying, inactivate slowly during maintained depolar...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Patel, Amanda J., Lauritzen, Inger, Lazdunski, Michel, Honoré, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792668/
https://ncbi.nlm.nih.gov/pubmed/9547220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-09-03117.1998
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