Involvement of cAMP-Dependent Protein Kinase in the Nucleus Accumbens in Cocaine Self-Administration and Relapse of Cocaine-Seeking Behavior

cAMP-dependent protein kinase (PKA) in the nucleus accumbens (NAc) has been implicated in cocaine addiction because (1) cocaine reinforcement is mediated by dopamine receptors that modulate cAMP formation, and (2) repeated exposure to cocaine upregulates the cAMP system in NAc neurons. This study te...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Self, David W., Genova, Lisa M., Hope, Bruce T., Barnhart, William J., Spencer, Jennifer J., Nestler, Eric J.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 1998
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792608/
https://ncbi.nlm.nih.gov/pubmed/9465009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-05-01848.1998
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