GABA(A) Receptor Pharmacology and Subtype mRNA Expression in Human Neuronal NT2-N Cells

Human NT2 teratocarcinoma cells differentiate into neuron-like NT2-N cells when treated with retinoic acid. GABA evoked concentration-dependent whole-cell currents in NT2-N cells with an EC(50) of 21.8 μm and a Hill slope of 1.2. GABA(A) receptor (GABAR) currents reversed atE(Cl−) and did not displa...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Neelands, Torben R., Greenfield, L. John, Zhang, Jie, Turner, R. Scott, Macdonald, Robert L.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 1998
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792560/
https://ncbi.nlm.nih.gov/pubmed/9634565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-13-04993.1998
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