PD‐L1 expression, CD8+ and CD4+ lymphocyte rate are predictive of pathological complete response after neoadjuvant chemoradiotherapy for squamous cell cancer of the thoracic esophagus

BACKGROUND: Neoadjuvant chemoradiotherapy (CTRT) can effectively downstage esophageal squamous cell carcinoma (SCC) in patients with locally advanced disease and prolonged survival have been observed in patients with a pathological complete response (ypCR). AIMS AND METHODS: This exploratory study a...

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Veröffentlicht in:Cancer Med
Hauptverfasser: Fassan, Matteo, Cavallin, Francesco, Guzzardo, Vincenza, Kotsafti, Andromachi, Scarpa, Melania, Cagol, Matteo, Chiarion‐Sileni, Vanna, Maria Saadeh, Luca, Alfieri, Rita, Castagliuolo, Ignazio, Rugge, Massimo, Castoro, Carlo, Scarpa, Marco
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Cancer Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792480/
https://ncbi.nlm.nih.gov/pubmed/31429521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2359
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