Use of a Mouse Model and Human Umbilical Vein Endothelial Cells to Investigate the Effect of Arsenic Exposure on Vascular Endothelial Function and the Associated Role of Calpains

BACKGROUND: Arsenic (As) is a well-known environmental contaminant. Chronic exposure to As is known to increase the risk of cardiovascular diseases, including atherosclerosis, hypertension, diabetes, and stroke. However, the detailed mechanisms by which As causes vascular dysfunction involving endot...

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Publicado no:Environ Health Perspect
Main Authors: Cai, Zhihui, Zhang, Yanqing, Zhang, Yutian, Miao, Xiaofeng, Li, Shu, Yang, Hui, Ling, Qinjie, Hoffmann, Peter R., Huang, Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: Environmental Health Perspectives 2019
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792366/
https://ncbi.nlm.nih.gov/pubmed/31274337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP4538
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