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Holistic optimization of an RNA-seq workflow for multi-threaded environments

SUMMARY: For many next generation-sequencing pipelines, the most computationally intensive step is the alignment of reads to a reference sequence. As a result, alignment software such as the Burrows-Wheeler Aligner is optimized for speed and is often executed in parallel on the cloud. However, there...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Hung, Ling-Hong, Lloyd, Wes, Agumbe Sridhar, Radhika, Athmalingam Ravishankar, Saranya Devi, Xiong, Yuguang, Sobie, Eric, Yeung, Ka Yee
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792127/
https://ncbi.nlm.nih.gov/pubmed/30859176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz169
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