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Radium 223-Mediated Zonal Cytotoxicity of Prostate Cancer in Bone
BACKGROUND: Bone-targeting radiotherapy with Radium-223 (Rad-223), a radioisotope emitting genotoxic alpha-radiation with limited tissue penetrance (∼100 µm), prolongs the survival of patients with metastatic prostate cancer (PCa). Confoundingly, the clinical response to Rad-223 is often followed by...
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| Veröffentlicht in: | J Natl Cancer Inst |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6792112/ https://ncbi.nlm.nih.gov/pubmed/30657953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djz007 |
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