Depletion of mitochondrial protease OMA1 alters proliferative properties and promotes metastatic growth of breast cancer cells

Metastatic competence of cancer cells is influenced by many factors including metabolic alterations and changes in mitochondrial biogenesis and protein homeostasis. While it is generally accepted that mitochondria play important roles in tumorigenesis, the respective molecular events that regulate a...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Daverey, Amita, Levytskyy, Roman M., Stanke, Kimberly M., Viana, Martonio Ponte, Swenson, Samantha, Hayward, Stephen L., Narasimhan, Madhusudhanan, Khalimonchuk, Oleh, Kidambi, Srivatsan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791882/
https://ncbi.nlm.nih.gov/pubmed/31611601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49327-2
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