1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol Attenuates Streptozotocin-Induced Pancreatic Beta Cell Damage by Promoting Glucose Transporter 2 Endocytosis

Streptozotocin (STZ) is widely used to induce diabetic rodent models. It is specifically toxic to pancreatic beta cells and causes severe destruction and dysfunction. We investigated the effect of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) on an STZ-induced diabetic mouse model. PLAG atten...

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Опубликовано в: :Mol Cell Biol
Главные авторы: Kim, Jimin, Kim, Joo Heon, Sohn, Ki-Young, Yoon, Sun Young, Kim, Jae Wha
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791655/
https://ncbi.nlm.nih.gov/pubmed/31481450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00157-19
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