Live-attenuated H1N1 influenza vaccine candidate displays potent efficacy in mice and ferrets

Currently, influenza vaccine manufacturers need to produce 1–5 x 10(7) PFU of each vaccine strain to fill one dose of the current live-attenuated-influenza-vaccine (LAIV). To make a single dose of inactivated vaccine (15 ug of each hemagglutinin), the equivalent of 10(10) PFU of each vaccine strains...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Stauft, Charles B., Yang, Chen, Coleman, J. Robert, Boltz, David, Chin, Chiahsuan, Kushnir, Anna, Mueller, Steffen
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791556/
https://ncbi.nlm.nih.gov/pubmed/31609986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223784
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