ANO4 (Anoctamin 4) Is a Novel Marker of Zona Glomerulosa That Regulates Stimulated Aldosterone Secretion

Microarray comparison of the transcriptomes of human adrenal zona glomerulosa (ZG) and zona fasciculata found several ZG-specific genes that negatively regulate aldosterone secretion. The third and most significantly upregulated ZG-gene (19.9-fold compared with zona fasciculata, P=6.58×10(−24)) was...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hypertension
Hauptverfasser: Maniero, Carmela, Scudieri, Paolo, Haris Shaikh, Lalarukh, Zhao, Wanfeng, Gurnell, Mark, Galietta, Luis J.V., Brown, Morris J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott, Williams & Wilkins 2019
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791498/
https://ncbi.nlm.nih.gov/pubmed/31564164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13287
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