Rap1 Negatively Regulates the Hippo Pathway to Polarize Directional Protrusions in Collective Cell Migration

In collective cell migration, directional protrusions orient cells in response to external cues, which requires coordinated polarity among the migrating cohort. However, the molecular mechanism has not been well defined. Drosophila border cells (BCs) migrate collectively and invade via the confined...

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Udgivet i:Cell Rep
Main Authors: Chang, Yu-Chiuan, Wu, Jhen-Wei, Hsieh, Yi-Chi, Huang, Tzu-Han, Liao, Zih-Min, Huang, Yi-Shan, Mondo, James A., Montell, Denise, Jang, Anna C.-C.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791367/
https://ncbi.nlm.nih.gov/pubmed/29466741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.01.080
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