Dimerization and phosphorylation of Lutheran/basal cell adhesion molecule are critical for its function in cell migration on laminin

Tumor cell migration depends on the interactions of adhesion proteins with the extracellular matrix. Lutheran/basal cell adhesion molecule (Lu/BCAM) promotes tumor cell migration by binding to laminin α5 chain, a subunit of laminins 511 and 521. Lu/BCAM is a type I transmembrane protein with a cytop...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Guadall, Anna, Cochet, Sylvie, Renaud, Olivier, Colin, Yves, Le Van Kim, Caroline, de Brevern, Alexandre G., El Nemer, Wassim
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791331/
https://ncbi.nlm.nih.gov/pubmed/31413112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007521
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