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High Expression of Serine Hydroxymethyltransferase 2 Indicates Poor Prognosis of Gastric Cancer Patients

BACKGROUND: Serine hydroxymethyltransferase (SHMT) is the enzyme that catalyzes the reversible conversion of serine to glycine and tetrahydrofolate-bound one-carbon unit. Upregulation of SHMT2 has been observed in a variety of cancers, but the expression profile and clinical value of SHMT2 in gastri...

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Détails bibliographiques
Publié dans:Med Sci Monit
Auteurs principaux: Shi, Haihong, Fang, Xiaoxu, Li, Yanfang, Zhang, Yingchun
Format: Artigo
Langue:Inglês
Publié: International Scientific Literature, Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791185/
https://ncbi.nlm.nih.gov/pubmed/31581160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.917435
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