METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer

BACKGROUND: As one of the most frequent chemical modifications in eukaryotic mRNAs, N6-methyladenosine (m6A) modification exerts important effects on mRNA stability, splicing, and translation. Recently, the regulatory role of m6A in tumorigenesis has been increasingly recognized. However, dysregulat...

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Veröffentlicht in:Mol Cancer
Hauptverfasser: Yue, Ben, Song, Chenlong, Yang, Linxi, Cui, Ran, Cheng, Xingwang, Zhang, Zizhen, Zhao, Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790244/
https://ncbi.nlm.nih.gov/pubmed/31607270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1065-4
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