F5-peptide enhances the efficacy of the non-hormonal male contraceptive adjudin

OBJECTIVE. The bioavailability of the non-hormonal male contraceptive adjudin is low in rats due to the blood-testis barrier (BTB). This study was designed to examine if F5-peptide, an endogenously produced reversible BTB modifier, could enhance the bioavailability of adjudin to affect spermatogenes...

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Udgivet i:Contraception
Main Authors: Chen, Haiqi, Mruk, Dolores, Wong, Chris K.C., Silvestrini, Bruno, Cheng, C. Yan
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790069/
https://ncbi.nlm.nih.gov/pubmed/30763581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.contraception.2019.01.007
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