Selective cadmium regulation mediated by a cooperative binding mechanism in CadR

Detoxification of the highly toxic cadmium element is essential for the survival of living organisms. Pseudomonas putida CadR, a MerR family transcriptional regulator, has been reported to exhibit an ultraspecific response to the cadmium ion. Our crystallographic and spectroscopic studies reveal tha...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Liu, Xichun, Hu, Qingyuan, Yang, Jinmei, Huang, Shanqing, Wei, Tianbiao, Chen, Weizhong, He, Yafeng, Wang, Dan, Liu, Zhijun, Wang, Kang, Gan, Jianhua, Chen, Hao
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789929/
https://ncbi.nlm.nih.gov/pubmed/31548408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908610116
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