Transcriptional control of lung alveolar type 1 cell development and maintenance by NK homeobox 2-1

The extraordinarily thin alveolar type 1 (AT1) cell constitutes nearly the entire gas exchange surface and allows passive diffusion of oxygen into the blood stream. Despite such an essential role, the transcriptional network controlling AT1 cells remains unclear. Using cell-specific knockout mouse m...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Little, Danielle R., Gerner-Mauro, Kamryn N., Flodby, Per, Crandall, Edward D., Borok, Zea, Akiyama, Haruhiko, Kimura, Shioko, Ostrin, Edwin J., Chen, Jichao
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789920/
https://ncbi.nlm.nih.gov/pubmed/31548395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906663116
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