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Targeting brain tumours: apoferritin nanocage for delivery of novel analogues of temozolomide

Treatment for glioblastoma multiforme (GBM) consists of surgery, radiotherapy and temozolomide (TMZ) chemotherapy. Nevertheless, patient prognosis remains poor; in England 5-year survival is < 10%. Resistance to TMZ is a major obstacle thwarting successful treatment, due to overexpression of the...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Bouzinab, Kaouthar, Thomas, Neil R, Turyanska, Lyudmila, Gershkovich, Pavel, Weston, Nicola, Ashford, Marianne B, Bradshaw, Tracey D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789696/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz167.015
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