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Characterisation of the anti-migratory activity of the 6-bromoindirubin-3’oxime (BIO) derivative VTIND42 in patient-derived GBM subpopulations

INTRODUCTION: Targeting the infiltrative nature of GBMs with anti-migratory drugs as combination treatment for prevention of tumour recurrence is an attractive disease management option. One such class of drugs are the GSK-3 inhibitors 6-bromoindirubin-3′-oximes (BIO). BIO has been proposed for use...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Peat, Samuel, Bruning-Richardson, Anke, Meijer, Laurent, Lawler, Sean, Thiéry, Valérie, Morton, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789683/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz167.026
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