Mutations in VP0 and 2C Proteins of Duck Hepatitis A Virus Type 3 Attenuate Viral Infection and Virulence

Duck hepatitis A virus (DHAV) is prevalent worldwide and has caused significant economic losses. As the predominant serotype in China, DHAV-3 has become a major challenge to the local duck industry. Here the genetics and pathogenesis of a virulent DHAV-3 strain and its embryo-passaged strain were as...

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Veröffentlicht in:Vaccines (Basel)
Hauptverfasser: Wen, Xingjian, Guo, Jinlong, Sun, Di, Wang, Mingshu, Cao, Dian, Cheng, Anchun, Zhu, Dekang, Liu, Mafeng, Zhao, Xinxin, Yang, Qiao, Chen, Shun, Jia, Renyong, Wu, Ying, Zhang, Shaqiu, Mao, Sai, Ou, Xumin, Chen, Xiaoyue, Yu, Yanling, Zhang, Ling, Liu, Yunya, Tian, Bin, Pan, Leichang, Rehman, Mujeeb Ur
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789628/
https://ncbi.nlm.nih.gov/pubmed/31514454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines7030111
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