Characterization of Monoclonal Antibodies against σA Protein and Cross-Reactive Epitope Identification and Application for Detection of Duck and Chicken Reovirus Infections

Although σA is an important major core protein of duck reovirus (DRV), the B-cell epitopes of this protein remain unknown to reseacrhers. Six monoclonal antibodies (MAbs) (1A7, 3F4, 5D2, 4E2, 3C7, and 2B7) were developed by using prokaryotic-expressed recombinant His-σA protein. Five of six MAbs (1A...

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Publicado no:Pathogens
Main Authors: Chen, Xueming, Li, Tongtong, Chen, Xiaodan, Li, Chenxi, Lin, Weiwei, Liu, Hongyu, Song, Shuping, Bai, Xiaofei, Zhang, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789564/
https://ncbi.nlm.nih.gov/pubmed/31500272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens8030140
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