An Attenuated Zika Virus Encoding Non-Glycosylated Envelope (E) and Non-Structural Protein 1 (NS1) Confers Complete Protection against Lethal Challenge in a Mouse Model

Zika virus (ZIKV), a mosquito-transmitted flavivirus, emerged in the last decade causing serious human diseases, including congenital microcephaly in newborns and Guillain-Barré syndrome in adults. Although many vaccine platforms are at various stages of development, no licensed vaccines are current...

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Pubblicato in:Vaccines (Basel)
Autori principali: Annamalai, Arun S., Pattnaik, Aryamav, Sahoo, Bikash R., Guinn, Zack P., Bullard, Brianna L., Weaver, Eric A., Steffen, David, Natarajan, Sathish Kumar, Petro, Thomas M., Pattnaik, Asit K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789518/
https://ncbi.nlm.nih.gov/pubmed/31547297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines7030112
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