High frequency of inactivating tetraspanin CD37 mutations in diffuse large B-cell lymphoma at immune-privileged sites

Tetraspanin CD37 is predominantly expressed on the cell surface of mature B lymphocytes and is currently being studied as novel therapeutic target for B-cell lymphoma. Recently, we demonstrated that loss of CD37 induces spontaneous B-cell lymphoma in Cd37-knockout mice and correlates with inferior s...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Elfrink, Suraya, de Winde, Charlotte M., van den Brand, Michiel, Berendsen, Madeleine, Roemer, Margaretha G. M., Arnold, Frank, Janssen, Luuk, van der Schaaf, Alie, Jansen, Erik, Groenen, Patricia J. T. A., Eijkelenboom, Astrid, Stevens, Wendy, Hess, Corine J., van Krieken, J. Han, Vermaat, Joost S. P., Cleven, Arjen H. G., de Groen, Ruben A. L., Neviani, Viviana, de Jong, Daphne, van Deventer, Sjoerd, Scheijen, Blanca, van Spriel, Annemiek B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789512/
https://ncbi.nlm.nih.gov/pubmed/31366619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019001185
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