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Unraveling Hepcidin Plasma Protein Binding: Evidence from Peritoneal Equilibration Testing

Peptide hormone hepcidin regulates systemic iron metabolism and has been described to be partially bound to α2-macroglobulin and albumin in blood. However, the reported degree of hepcidin protein binding varies between <3% and ≈89%. Since protein-binding may influence hormone function and quantif...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Diepeveen, Laura E., Laarakkers, Coby M., Peters, Hilde P.E., van Herwaarden, Antonius E., Groenewoud, Hans, IntHout, Joanna, Wetzels, Jack F., van Swelm, Rachel P.L., Swinkels, Dorine W.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789442/
https://ncbi.nlm.nih.gov/pubmed/31450766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12030123
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