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Overexpression of Rad51 predicts poor prognosis and silencing of Rad51 increases chemo-sensitivity to doxorubicin in neuroblastoma

Outcome for children with high-risk neuroblastoma (NB) remains suboptimal. Recurrence and metastasis caused by chemo-resistance is an underlying mechanism contributing to the poor prognosis. Aberrant expression of Rad51 is implicated in both radio- and chemo-sensitivity in many human malignancies. H...

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Détails bibliographiques
Publié dans:Am J Transl Res
Auteurs principaux: Xu, Yonghu, Chen, Kai, Cai, Yuanxia, Cheng, Cheng, Zhang, Zihan, Xu, Guofeng
Format: Artigo
Langue:Inglês
Publié: e-Century Publishing Corporation 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789219/
https://ncbi.nlm.nih.gov/pubmed/31632548
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