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Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide

The filamentous bacteriophage fd bind a cell target with exquisite specificity through its few copies of display peptides, whereas nanoparticles functionalized with hundreds to thousands of synthetically generated phage display peptides exhibit variable and often-weak target binding. We hypothesise...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Wu, Lin-Ping, Ahmadvand, Davoud, Su, Junan, Hall, Arnaldur, Tan, Xiaolong, Farhangrazi, Z. Shadi, Moghimi, S. Moein
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789111/
https://ncbi.nlm.nih.gov/pubmed/31604928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12554-2
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