Cis-regulatory CYP6P9b P450 variants associated with loss of insecticide-treated bed net efficacy against Anopheles funestus

Elucidating the genetic basis of metabolic resistance to insecticides in malaria vectors is crucial to prolonging the effectiveness of insecticide-based control tools including long lasting insecticidal nets (LLINs). Here, we show that cis-regulatory variants of the cytochrome P450 gene, CYP6P9b, ar...

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Udgivet i:Nat Commun
Main Authors: Mugenzi, Leon M. J., Menze, Benjamin D., Tchouakui, Magellan, Wondji, Murielle J., Irving, Helen, Tchoupo, Micareme, Hearn, Jack, Weedall, Gareth D., Riveron, Jacob M., Wondji, Charles S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789023/
https://ncbi.nlm.nih.gov/pubmed/31604938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12686-5
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