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ESR1 Mutations in Breast Cancer
The acquisition of ligand-independent ESR1 mutations during aromatase inhibitor (AI) therapy in metastatic estrogen receptor (ER)-positive breast cancer is a common mechanism of hormonal therapy resistance. Preclinical and clinical studies have demonstrated that ESR1 mutations can pre-exist in prima...
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| Publicado no: | Cancer |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6788940/ https://ncbi.nlm.nih.gov/pubmed/31318440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32345 |
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