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Heart disease in a mutant mouse model of spontaneous eosinophilic myocarditis maps to three loci

BACKGROUND: Heart disease (HD) is the major cause of morbidity and mortality in patients with hypereosinophilic diseases. Due to a lack of adequate animal models, our understanding of the pathophysiology of eosinophil-mediated diseases with heart complications is limited. We have discovered a mouse...

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Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Zimmermann, Nives, Gibbons, William J., Homan, Shelli M., Prows, Daniel R.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6788080/
https://ncbi.nlm.nih.gov/pubmed/31601172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6108-0
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