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Metastatic renal cell carcinoma cells growing in 3D on poly-D-lysine or laminin present a stem-like phenotype and drug resistance

3D spheroids are built by heterogeneous cell types in different proliferative and metabolic states and are enriched in cancer stem cells. The main aim of the study was to investigate the usefulness of a novel metastatic renal cell carcinoma (RCC) 3D spheroid culture for in vitro cancer stem cell phy...

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Bibliografiske detaljer
Udgivet i:Oncol Rep
Main Authors: Brodaczewska, Klaudia K., Bielecka, Zofia F., Maliszewska-Olejniczak, Kamila, Szczylik, Cezary, Porta, Camillo, Bartnik, Ewa, Czarnecka, Anna M.
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6788014/
https://ncbi.nlm.nih.gov/pubmed/31545459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2019.7321
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