Dietary intakes and biomarker patterns of folate, vitamin B(6), and vitamin B(12) can be associated with cognitive impairment by hypermethylation of redox-related genes NUDT15 and TXNRD1

BACKGROUND: B vitamins in the one-carbon metabolism pathway (folate, vitamin B(6), and vitamin B(12)) have been implicated in DNA methylation, and their deficiency may contribute to cognitive decline through increased homocysteine (Hcy) levels and subsequent oxidative damage. The aim of this study w...

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Dettagli Bibliografici
Pubblicato in:Clin Epigenetics
Autori principali: An, Yu, Feng, Lingli, Zhang, Xiaona, Wang, Ying, Wang, Yushan, Tao, Lingwei, Qin, Zhongsheng, Xiao, Rong
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787977/
https://ncbi.nlm.nih.gov/pubmed/31601260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0741-y
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