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Dietary intakes and biomarker patterns of folate, vitamin B(6), and vitamin B(12) can be associated with cognitive impairment by hypermethylation of redox-related genes NUDT15 and TXNRD1

BACKGROUND: B vitamins in the one-carbon metabolism pathway (folate, vitamin B(6), and vitamin B(12)) have been implicated in DNA methylation, and their deficiency may contribute to cognitive decline through increased homocysteine (Hcy) levels and subsequent oxidative damage. The aim of this study w...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: An, Yu, Feng, Lingli, Zhang, Xiaona, Wang, Ying, Wang, Yushan, Tao, Lingwei, Qin, Zhongsheng, Xiao, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787977/
https://ncbi.nlm.nih.gov/pubmed/31601260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0741-y
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