Co‐mutational assessment of circulating tumour DNA (ctDNA) during osimertinib treatment for T790M mutant lung cancer

Osimertinib is designed to target the secondary resistant EGFR T790M mutant and has shown outstanding clinical efficacy. However, the prognostic prediction of osimertinib patients is a big problem in clinical practice. The resistance mechanism of osimertinib is also not fully understood. NGS and a 1...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Xing, Puyuan, Han, Xiaohong, Wang, Sha, Liu, Yutao, Yang, Sheng, Hao, Xuezhi, Wang, Yan, Liu, Peng, Li, Junling, Wang, Lin, Chang, Lianpeng, Guan, Yanfang, Zhang, Zhishang, Wu, Di, Yao, Jiarui, Yi, Xin, Shi, Yuankai
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787503/
https://ncbi.nlm.nih.gov/pubmed/31393074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14565
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