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Light-induced Nrf2(−/−) mice as atrophic age-related macular degeneration model and treatment with nanoceria laden injectable hydrogel
Elevated oxidative stress and associated reactive oxygen species (ROS) accumulation are hallmarks in the induction and progression of age-related macular degeneration (AMD). By exposing nuclear factor erythroid 2-related factor (Nrf2) knockout (Nrf2(−/−)) mice to mild white light, we were able to ge...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6787253/ https://ncbi.nlm.nih.gov/pubmed/31601909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51151-7 |
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