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Allosteric activation of an ion channel triggered by modification of mechanosensitive nano-pockets

Lipid availability within transmembrane nano-pockets of ion channels is linked with mechanosensation. However, the effect of hindering lipid-chain penetration into nano-pockets on channel structure has not been demonstrated. Here we identify nano-pockets on the large conductance mechanosensitive cha...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Kapsalis, Charalampos, Wang, Bolin, El Mkami, Hassane, Pitt, Samantha J., Schnell, Jason R., Smith, Terry K., Lippiat, Jonathan D., Bode, Bela E., Pliotas, Christos
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787021/
https://ncbi.nlm.nih.gov/pubmed/31601809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12591-x
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