BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma

Despite advances in therapy, glioblastoma remains an incurable disease with a dismal prognosis. Recent studies have implicated cancer stem cells within glioblastoma (glioma stem cells, GSCs) as mediators of therapeutic resistance and tumor progression. In this study, we investigated the role of the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sachdeva, Rohit, Wu, Megan, Johnson, Kevin, Kim, Hyunsoo, Celebre, Angela, Shahzad, Uswa, Graham, Maya Srikanth, Kessler, John A., Chuang, Jeffrey H., Karamchandani, Jason, Bredel, Markus, Verhaak, Roel, Das, Sunit
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787003/
https://ncbi.nlm.nih.gov/pubmed/31602000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51270-1
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