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Challenges and Opportunities for Therapeutics Targeting the Voltage-Gated Sodium Channel Isoform Na(V)1.7
Voltage-gated sodium ion channel subtype 1.7 (Na(V)1.7) is a high interest target for the discovery of non-opioid analgesics. Compelling evidence from human genetic data, particularly the finding that persons lacking functional Na(V)1.7 are insensitive to pain, has spurred considerable effort to dev...
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| Publicado no: | J Med Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6786914/ https://ncbi.nlm.nih.gov/pubmed/31012583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.8b01906 |
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