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Ferritin heavy chain protects the developing wing from reactive oxygen species and ferroptosis

The interplay between signalling pathways and metabolism is crucial for tissue growth. Yet, it remains poorly understood. Here, we studied the consequences of modulating iron metabolism on the growth of Drosophila imaginal discs. We find that reducing the levels of the ferritin heavy chain in the la...

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Publicat a:PLoS Genet
Autors principals: Mumbauer, Simone, Pascual, Justine, Kolotuev, Irina, Hamaratoglu, Fisun
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786644/
https://ncbi.nlm.nih.gov/pubmed/31568497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008396
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