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Activity-based DNA-encoded library screening

Robotic high-throughput compound screening (HTS) and, increasingly, DNA-encoded library (DEL) screening are driving bioactive chemical matter discovery in the post-genome era. HTS enables activity-based investigation of highly complex targets using static compound libraries. Conversely, DEL grants e...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:ACS Comb Sci
Main Authors: Cochrane, Wesley G., Malone, Marie L., Dang, Vuong Q., Cavett, Valerie, Satz, Alexander L., Paegel, Brian M.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786493/
https://ncbi.nlm.nih.gov/pubmed/30884226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.9b00037
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