Effects of Naloxegol on Gastrointestinal Transit and Colonic Fecal Volume in Healthy Participants Receiving Oxycodone

BACKGROUND/AIMS: Opioids cause gastrointestinal (GI) dysmotility, decrease gut secretion, and affect gut sphincters. Symptoms of opioid-induced bowel dysfunction may be alleviated by peripherally acting opioid antagonists like naloxegol, but detailed knowledge on GI effects of this drug is lacking....

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Detalles Bibliográficos
Publicado en:J Neurogastroenterol Motil
Main Authors: Olesen, Anne E, Grønlund, Debbie, Mark, Esben B, Krogh, Klaus, Frøkjær, Jens B, Drewes, Asbjørn M
Formato: Artigo
Idioma:Inglês
Publicado: Korean Society of Neurogastroenterology and Motility 2019
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786453/
https://ncbi.nlm.nih.gov/pubmed/31587551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5056/jnm18079
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