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Propofol decreases the excitability of cholinergic neurons in mouse basal forebrain via GABA(A) receptors

Propofol is an intravenous anesthetic that can active γ-aminobutyric acid A (GABA(A)) receptors and generate sedative–hypnotic effects. Propofol has been widely applied clinically to achieve sedation comparable to sleep in humans. The basal forebrain (BF) is a brain region that plays an important ro...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Chen, Lei, Yang, Zhi-lai, Cheng, Juan, Zhang, Ping-ping, Zhang, Le-sha, Liu, Xue-sheng, Wang, Lie-cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786414/
https://ncbi.nlm.nih.gov/pubmed/30367153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0168-6
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